Chris Pastore

Chris comes to Penn after spending his undergraduate years at the University of Pittsburgh where he studied Microbiology.  He has previously looked at the microbiome of some of the Lingo receptor knockout mice as well as re-developed multiple allergy models for the lab. He shifts around helping multiple projects such as work on cellular sources of IL-33, and culturing human macrophages. He currently heads a project looking at helminth-infected humans and levels of trefoils.

Where are you from?
Holmes, PA.

What is your favorite hangout place or favorite thing to do?
Chris enjoys training for and running road races. He is also an avid golfer and skier. And when its time to relax, he enjoys craft beer and reading or watching Sci-Fi/Fantasy.

What is your prior degree/training?
B.S. in Microbiology, University of Pittsburgh

What is your career aspiration?
Currently I am using my experience in the Herbert lab to see where I want to go with my career.

Email address: pastorec@vet.upenn.edu

Updates on My Projects

My main project in lab involves studying global human immune responses to helminths in collaboration with the Nigerian Institute for Medical Research. This includes working with some human patient samples from our collaborators. The samples are from school aged children who are either infected or uninfected with different helminths. This work has also led me to some cell culture work with a human macrophage line to look at myeloid cytokine responses.

I am also working a project that looks at the role of cell-specific IL-33 in the context of colitis or in the context of a Nippostrongylus infection.

In the past I have collaborated with Dan Beiting of Penn to develop a microbiome profile of some of our mice. He has a great blog that I was able to utilize to help a somewhat inexperienced coder along the process of using some of the software required to generate this data. The link to his blog can be found here: Cloud computing for metagenomics – Part I

I have re-established allergy models for papain and house dust mite (HDM) for the lab.  The lab has a few outlets potentially into lung epithelium and currently we run a core that measures lung functionality.